Studies on the epidemiology of colitis due to Clostridium difficile in hamsters.
Studies on the epidemiology of colitis due to Clostridium difficile in hamsters.
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仓鼠艰难梭菌结肠炎的流行病学研究。
DOI：
10.1093/infdis/143.1.51
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Kim,KH
中科院分区：
文献类型：
--
作者：
Toshniwal,R;SilvaJr,J;Fekety,R;Kim,KH
用万古霉素治疗的仓鼠在常规动物室中比在设计防止艰难梭菌交叉感染的房间中更容易发生肠结肠炎。解析：选c。与笼子、食物架、地板、水桶、饲养员的手和患有小肠结肠炎的动物的粪便隔离，但与未经处理的仓鼠、空气或新鲜打开的袋子中的食物隔离。在洁净室中没有将困难与环境源隔离。不可能确定这种有机体的哪一种来源对其传播最重要。同。圣山的相互传染困难可能在仓鼠菌落抗生素相关性小肠结肠炎的发病机制中起重要作用。
Hamsters treated with vancomycin developed enterocolitis significantly more often in a conventional animal room than in a room designed to prevent cross-infection withClostridium difficile. In the conventional roomC. difficilewas isolated from cages, food racks, floors, buckets, the hands of caretakers, and the stools of animals with enterocolitis but not from untreated hamsters, air, or food from freshly opened bags.C. difficilewas not isolated from environmental sources in the clean room. It was not possible to determine which of the sources of the organism was most important in its spread. Cross-infection withC. difficilemay be important in the pathogenesis of antibiotic-associated enterocolitis in hamster colonies.