Optimization of a waveguide-mode sensing chip for an ultraviolet near-field illumination biosensor.
Optimization of a waveguide-mode sensing chip for an ultraviolet near-field illumination biosensor.
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DOI：
10.1364/oe.25.026011
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发表时间：
2017-10
期刊：
影响因子：
3.8
通讯作者：
Chiaki Kuroda;Y. Ohki;M. Fujimaki
中科院分区：
文献类型：
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作者：
Chiaki Kuroda;Y. Ohki;M. Fujimaki
由两个波导层和一个玻璃基板组成的平面传感芯片波导模式传感器是一种很有前途的近场照明生物传感器。针对紫外光诱导的荧光标记，基于数值计算揭示的紫外近场光增强机理，优化了波导模式传感芯片的结构。并提出了最佳候选材料。如上所述优化的芯片应该能够将紫外线近场光的强度提高到铝表面等离子体共振传感芯片的25倍。
A waveguide-mode sensor with a planar sensing chip, consisting of two waveguiding layers and a glass substrate, is a promising candidate for a near-field illumination biosensor. Aiming at using fluorescent labeling induced by ultraviolet light, we optimize the structure of a waveguide-mode sensing chip, based on the mechanism for enhancing ultraviolet near-field light revealed by numerical calculations. Candidates of optimal materials are also presented. The chip optimized as above should be able to enhance the intensity of ultraviolet near-field light 25 times as high as an Al surface plasmon resonance sensing chip.