Transcriptional and epigenetic regulation of autophagy in plants
Transcriptional and epigenetic regulation of autophagy in plants
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植物自噬的转录和表观遗传调控
DOI：
10.1016/j.tig.2020.06.013
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发表时间：
2020
影响因子：
11.4
通讯作者：
Caiji Gao
中科院分区：
文献类型：
--
作者：
Chao Yang;Ming Luo;Xiaohong Zhuang;Faqiang Li;Caiji Gao
自噬是一种高度保守的质量控制机制，对维持细胞动态平衡和植物的健康生长至关重要。与细胞质控制自噬的广泛研究相比，涉及植物自噬调控的核事件的研究才刚刚开始。越来越多的证据揭示了植物自噬基因的协调表达，以响应不同的发育状态和生长条件。在这里，我们总结了在鉴定与植物自噬过程相关的严格控制的转录因子和组蛋白标记方面的最新进展，并提出了由转录调节因子和表观遗传修饰物组成的几个模块，作为重要的核角色，可能有助于在转录和转录后水平上对植物自噬进行短期和长期的控制。
Autophagy, a highly conserved quality control mechanism, is essential for maintaining cellular homeostasis and healthy growth of plants. Compared with extensive research in the cytoplasmic control of autophagy, studies regarding the nuclear events involved in the regulation of plant autophagy are just beginning to emerge. Accumulating evidence reveals a coordinated expression of plant autophagy genes in response to diverse developmental states and growth conditions. Here, we summarize recent progress in the identification of tightly controlled transcription factors and histone marks associated with the autophagic process in plants, and propose several modules, consisting of transcription regulators and epigenetic modifiers, as important nuclear players that could contribute to both short-term and long-term controls of plant autophagy at the transcriptional and post-transcriptional levels.