Alteration of Platelet Aggregation by Cigarette Smoke and Carbon Monoxide

Alteration of Platelet Aggregation by Cigarette Smoke and Carbon Monoxide
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香烟烟雾和一氧化碳对血小板聚集的改变

DOI:
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发表时间:
1982
影响因子:
6.7
通讯作者:
Carol Perry
Carol Perry
中科院分区:
医学2区
文献类型:
--
作者:
A. Mansouri;Carol Perry

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摘要 在香烟烟雾和一氧化碳存在的情况下研究了肾上腺素、二磷酸腺苷和花生四烯酸的血小板聚集。结果表明,香烟烟雾抑制花生四烯酸诱导的血小板聚集以及肾上腺素诱导的第二阶段聚集。二磷酸腺苷诱导的血小板聚集不受香烟烟雾的显着影响。一氧化碳会引起血小板聚集的类似变化。这些结果表明香烟烟雾抑制血小板聚集。这种聚集抑制是由于一氧化碳的存在。
Summary Platelet aggregation with epinephrine, adenosine diphosphate and arachidonic acid was studied in the presence of cigarette smoke and carbon monoxide. It is shown that cigarette smoke inhibits the arachidonic acid induced platelet aggregation as well as the second phase of epinephrine induced aggregation. The adenosine diphosphate induced platelet aggregation is not significantly affected by cigarette smoke. Carbon monoxide causes similar alterations in platelet aggregation. These results suggest that cigarette smoke inhibits platelet aggregation. This aggregation inhibition is due to the presence of carbon monoxide.
人血小板膜相关 NADH 依赖性细胞色素 C 还原酶的表征。
DOI: 10.1016/0049-3848(81)90234-6
发表时间: 1981
影响因子: 7.5
作者:
Moroff,G;Kosow,DP
通讯作者: Kosow,DP