Hybrid radiosity-SP3 equation based bioluminescence tomography reconstruction for turbid medium with low- and non-scattering regions
Hybrid radiosity-SP3 equation based bioluminescence tomography reconstruction for turbid medium with low- and non-scattering regions
复制标题
基于混合光能传递-SP3方程的生物发光断层扫描重建具有低散射和非散射区域的混浊介质
DOI：
10.1063/1.4862166
复制
发表时间：
2014-01-14
影响因子：
3.2
通讯作者：
Liang, Jimin
中科院分区：
文献类型：
--
作者：
Chen, Xueli;Zhang, Qitan;Liang, Jimin
针对胃癌检测中低散射区与高散射区和非散射区同时存在的问题，提出了一种基于辐射度-SP3方程的混合重建算法.该算法将三阶简化球谐近似（SP3）与辐射度方程相结合来描述生物发光光在生物组织中的传播，对低散射区和非散射区的混浊介质均具有可接受的精度。该算法的性能进行了评估与数字鼠标为基础的模拟和胃癌荷瘤小鼠为基础的原位实验。初步结果表明，该算法的可行性和优越性的混浊介质的低散射和非散射区域。(C)2014 AIP Publishing LLC.
To provide an ideal solution for a specific problem of gastric cancer detection in which low-scattering regions simultaneously existed with both the non- and high-scattering regions, a novel hybrid radiosity-SP3 equation based reconstruction algorithm for bioluminescence tomography was proposed in this paper. In the algorithm, the third-order simplified spherical harmonics approximation (SP3) was combined with the radiosity equation to describe the bioluminescent light propagation in tissues, which provided acceptable accuracy for the turbid medium with both low- and non-scattering regions. The performance of the algorithm was evaluated with digital mouse based simulations and a gastric cancer-bearing mouse based in situ experiment. Primary results demonstrated the feasibility and superiority of the proposed algorithm for the turbid medium with low- and non-scattering regions. (C) 2014 AIP Publishing LLC.