Spared short-term memory in monkeys following medial temporal lobe lesions is not yet established: a reply to Alvarez-Royo, Zola-Morgan and Squire.
Spared short-term memory in monkeys following medial temporal lobe lesions is not yet established: a reply to Alvarez-Royo, Zola-Morgan and Squire.
复制标题
内侧颞叶损伤后猴子的短期记忆尚不明确：对 Alvarez-Royo、Zola-Morgan 和 Squire 的答复。
DOI：
10.1016/0166-4328(93)90152-g
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发表时间：
1993
影响因子：
2.7
通讯作者：
Ringo,JL
中科院分区：
文献类型：
--
作者：
Ringo,JL
重要的是要知道是否短期记忆（STM）是保存在猴子，有时声称，损害内侧颞叶，破坏长期记忆。如本文所述，延迟匹配样本任务中的长期缺陷的大小与短延迟下的较慢学习密切相关。这种具有短暂延迟的学习缺陷可能是严重的，例如，尽管试验次数是对照组动物的10倍，但未能达到标准，但相同的动物可以正常进行一些视觉辨别。因此，这种缓慢的学习可能是最吝啬地归因于短时记忆缺陷。研究还审查比较延迟（非）匹配到样本的性能在病变的猴子在短期和长期的延迟。对于那些在所有延迟中接受同等培训的群体，短期赤字与长期赤字一样大。对于那些只在短期内接受培训的群体，短期赤字很小。对未来研究的注意事项进行了讨论。
It is important to know whether or not short-term memory (STM) is preserved in monkeys, as sometimes claimed, following lesions to medial temporal lobe that disrupt longer term memory. As examined herein, the magnitude of the longer term deficit in the delayed matching-to-sample task is well correlated with slower learning at short delays. This learning deficiency with short delays can be severe, e.g., failure to reach criterion despite ten times the number of trials required by control animals, yet the same animals can perform some visual discriminations normally. Such slow learning may thus be most parsimoniously attributed to a STM deficit. Studies are also reviewed which compare delayed (non)matching-to-sample performance in lesioned monkeys at short and long delays. For those groups that received equal training at all delays, the short-term deficit is as large as the longer term deficit. For those groups trained only at the short delay the short-term deficit is small. Caveats for future studies are discussed.