The neoglycolipid (NGL)-based oligosaccharide microarray system poised to decipher the meta-glycome.
The neoglycolipid (NGL)-based oligosaccharide microarray system poised to decipher the meta-glycome.
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DOI：
10.1016/j.cbpa.2014.01.007
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发表时间：
2014-02
影响因子：
7.8
通讯作者：
Liu, Yan
中科院分区：
文献类型：
--
作者：
Palma, Angelina S.;Feizi, Ten;Childs, Robert A.;Chai, Wengang;Liu, Yan
The neoglycolipid (NGL) technology is the basis of a state-of-the-art oligosaccharide microarray system. The NGL-based microarray system in the Glycosciences Laboratory Imperial College London (http://www3.imperial.ac.uk/glycosciences), is one of the two leading platforms for glycan microarrays, being offered for screening analyses to the broad biomedical community. Highlighted in this review are the sensitivity of the analysis system and, coupled with mass spectrometry, the provision for generating ‘designer’ microarrays from glycomes to identify novel ligands of biological relevance. Among recent applications are: assignments of ligands for apicomplexan parasites, pandemic 2009 influenza virus, polyoma and reoviruses, an innate immune receptor against fungal pathogens, Dectin-1, and a novel protein of the endoplasmic reticulum, malectin; also the characterization of an elusive cancer-associated antigen. Some other contemporary advances in glycolipid-containing arrays and microarrays are also discussed.
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影响因子：
6.7
作者：
Lai L;Bumstead J;Liu Y;Garnett J;Campanero-Rhodes MA;Blake DP;Palma AS;Chai W;Ferguson DJ;Simpson P;Feizi T;Tomley FM;Matthews S
通讯作者：
Matthews S
影响因子：
4.8
作者：
Marchant, Jan;Cowper, Ben;Matthews, Stephen
通讯作者：
Matthews, Stephen
DOI：
10.1084/jem.20120423
发表时间：
2012-07-30
期刊：
The Journal of experimental medicine
影响因子：
--
作者：
Klein F;Gaebler C;Mouquet H;Sather DN;Lehmann C;Scheid JF;Kraft Z;Liu Y;Pietzsch J;Hurley A;Poignard P;Feizi T;Morris L;Walker BD;Fätkenheuer G;Seaman MS;Stamatatos L;Nussenzweig MC
通讯作者：
Nussenzweig MC
影响因子：
6.7
作者：
Neu, Ursula;Allen, Stacy-ann A.;Stehle, Thilo
通讯作者：
Stehle, Thilo
影响因子：
46.9
作者：
Fukui, S;Feizi, T;Chai, WG
通讯作者：
Chai, WG