TREATMENT OF BABESIA GIBSONI INFECTIONS WITH PHENAMIDINE ISETHIONATE
TREATMENT OF BABESIA GIBSONI INFECTIONS WITH PHENAMIDINE ISETHIONATE
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DOI：
10.1136/vr.86.1.8
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发表时间：
1970-01-01
影响因子：
2.2
通讯作者：
VANNIASINGHAM, JA
中科院分区：
文献类型：
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作者：
GROVES, MG;VANNIASINGHAM, JA
三只狗进行实验，两只狗进行自然B.用 5 或 7'5 mg/lb 体重单次皮下注射剂量的非那脒治疗吉布森感染。或连续几天服用两次 7'5 毫克/磅的剂量。该药物在治疗临床感染方面是有效的，因为所有狗在治疗后72小时或更短的时间内寄生虫血症明显持续减少，但并没有完全消除寄生虫。最佳剂量是连续几天 7'5 毫克/磅（16 毫克/公斤）。
Three dogs with experimental and two with naturalB. gibsoniinfections were treated either with a single s/c dose of phenamidine at 5 or 7'5 mg/lb body wt. or two doses of 7'5 mg/lb on consecutive days. The drug was effective in treating clinical infection, because all dogs showed a definite and continuous decrease in parasitaemia 72 hours or less after treatment, but complete elimination of the parasites was not obtained. The best dosage was 7'5 mg/lb (16 mg/kg) on consecutive days.