Study of streptavidin coated onto PAMAM dendrimer modified magnetite nanoparticles
Study of streptavidin coated onto PAMAM dendrimer modified magnetite nanoparticles
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DOI：
10.1016/j.jmmm.2005.01.042
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发表时间：
2005-05-01
影响因子：
2.7
通讯作者：
Gu, HC
中科院分区：
文献类型：
--
作者：
Gao, F;Pan, BF;Gu, HC
在氨基硅烷修饰的磁性纳米粒子表面合成了聚酰胺-胺树枝状大分子。在将链霉亲和素涂覆到这些树枝状聚合物改性的磁铁矿纳米颗粒上后，与仅用氨基硅烷改性的磁铁矿纳米颗粒相比，测量到高达3.4倍的量的链霉亲和素（SA）。SA的生物素结合能力，从而增加树枝状大分子修饰后。(c)2005 Elsevier B. V.保留所有权利。
Polyamidoamine dendrimer was synthesized on the surface of amino silane modified magnetite nanoparticles. After coating of streptavidin to these dendrimer-modified magnetite nanoparticles, an up to 3.4 times higher amount of streptavidin (SA) was measured compared to magnetite nanoparticles modified with only amino silane. The biotin-binding capacity of SA thus increased after dendrimer modification. (c) 2005 Elsevier B.V. All rights reserved.