Atomic force microscopy of conventional and unconventional nucleic acid structures.
Atomic force microscopy of conventional and unconventional nucleic acid structures.
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常规和非常规核酸结构的原子力显微镜。
DOI：
10.1111/j.1365-2818.1992.tb03220.x
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发表时间：
1992
影响因子：
2
通讯作者：
Henderson,E
中科院分区：
文献类型：
--
作者：
Henderson,E
通过原子力显微镜获得了常规（沃森-克里克碱基配对）和非常规（G4 RNA）核酸结构的图像。这些图像可从沉积在新切割云母上的样品中重现。在这两种情况下观察到的纤维中都有明显的周期性亚结构特征。在G4 RNA的情况下，观察到尖端诱导的大纤维形成。
Images of conventional (Watson–Crick base paired) and unconventional (G4 RNA) nucleic acid structures have been obtained by atomic force microscopy. The images are reproducibly generated from samples deposited on freshly cleaved mica. Periodic substructural features are evident in fibres observed in both cases. In the case of G4 RNA, tip‐induced formation of large fibres is observed.