Photoinduced decarboxylative azidation of cyclic amino acids.
Photoinduced decarboxylative azidation of cyclic amino acids.
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DOI：
10.1039/c8ob02702a
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发表时间：
2019-02
影响因子：
3.2
通讯作者：
David C Marcote;Rosie Street-Jeakings;Elizabeth M Dauncey;James J. Douglas;A. Ruffoni;Daniele Leonori
中科院分区：
文献类型：
--
作者：
David C Marcote;Rosie Street-Jeakings;Elizabeth M Dauncey;James J. Douglas;A. Ruffoni;Daniele Leonori
通过可见光介导的有机光氧化还原催化，实现了环α-氨基酸的直接脱羧叠氮化反应。这种合成策略可以简单地制备含叠氮化物的构建块，并已用于两个二肽的n端脯氨酸残基的选择性修饰。
The direct decarboxylative azidation of cyclic α-amino acids has been achieved via visible light-mediated organo-photoredox catalysis. This synthetic strategy allows the simple preparation of azide-contaning building blocks and has been used in the selective modification of N-terminal proline residues of two di-peptides.