Reactivity of monoclonal antibody OKM5 with sebaceous carcinoma

Reactivity of monoclonal antibody OKM5 with sebaceous carcinoma
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单克隆抗体OKM5与皮脂腺癌的反应性

DOI:
10.1111/j.1600-0560.1991.tb01543.x
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发表时间:
1991
影响因子:
1.7
通讯作者:
Chundi He
Chundi He
中科院分区:
医学4区
文献类型:
--
作者:
Yuming Zhao;Hongduo Chen;Chundi He

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两例皮脂腺癌(SC),以及上皮肿瘤,黑色素瘤和淋巴瘤,使用免疫过氧化物酶和一组单克隆抗体在低温切片上进行检查。结果表明,在这两种情况下,所有SC细胞都与单克隆抗体OK反应强烈。M5,其他肿瘤细胞(幼代黄色肉芽肿细胞除外)则没有。SC表皮内的页状细胞也与OKM5抗体发生反应。虽然这种现象的性质值得进一步研究,但这种反应性或交叉反应性可能有助于SC的诊断。
Two cases of sebaceous carcinoma (SC), as well as epithelial tumours, melanoma, and lymphoma, were examined using immunoperoxidase and a panel of monoclonal antibodies on cryostat sections. The results showed that, whereas all SC cells in both cases reacted strongly with monoclonal antibody OK.M5, other tumour cells (except juvenile xanthogranuloma cells) did not. The pagetoid cells within the epidermis of SC also reacted with OKM5 antibody. Although the nature of the phenomenon merits further study, this reactivity, or cross‐reactivity, might possibly aid diagnosis of SC.
单克隆抗人单核细胞抗体 OKM1 和 OKM5 具有独特的组织分布,包括与血管内皮的不同反应性。
DOI: --
发表时间: 1984
期刊: Journal of immunology (Baltimore, Md. : 1950)
影响因子: --
作者:
Knowles2nd,DM;Tolidjian,B;Marboe,C;D'Agati,V;Grimes,M;Chess,L
通讯作者: Chess,L
由单克隆抗体定义的人类单核细胞的功能子集:单核细胞的独特子集包含能够诱导自体混合淋巴细胞培养物的细胞。
DOI: --
发表时间: 1983
期刊: Journal of immunology (Baltimore, Md. : 1950)
影响因子: --
作者:
Shen,HH;Talle,MA;Goldstein,G;Chess,L
通讯作者: Chess,L