Impact of adult spinal deformity corrective surgery in patients with the symptoms of gastroesophageal reflux disease: a 5-year follow-up report
Impact of adult spinal deformity corrective surgery in patients with the symptoms of gastroesophageal reflux disease: a 5-year follow-up report
复制标题
DOI：
10.1007/s00586-020-06300-2
复制
发表时间：
2020-04-01
影响因子：
2.8
通讯作者：
Matsuyama, Yukihiro
中科院分区：
文献类型：
--
作者：
Hasegawa, Tomohiko;Ushirozako, Hiroki;Matsuyama, Yukihiro
目的胃食管反流病（GERD）是成人脊柱畸形（ASD）的症状之一。对于ASD手术后反流症状的中长期改善知之甚少。因此，本研究从前瞻性收集的数据库中进行回顾性研究，旨在调查ASD矫正手术后至少2年内患者的反流d症状。方法采用胃食管反流症状频率量表（FSSG）对230例接受ASD手术的患者（平均年龄64岁）进行诊断。术前、术后6个月、1年、2年、5年分别观察FSSG评分和影像学参数。结果90例（39%）患者术前FSSG评分>= 8分诊断为GERD。x线检查结果显示矫正手术改善了局部和整体矫正。GERD患者术前FSSG评分（16.1 +/- 7.3分）在术后6个月内显著提高至7.7 +/- 7.4分（p < 0.001），术后FSSG评分维持在1年（9.9 +/- 8.2分，p = 0.061）、2年（9.7 +/- 8.2分，p = 0.086）、5年（9.4 +/- 8.0分，p = 0.177）。在GERD组中，62例患者（69%；改善病例）在术后6个月内FSSG评分< 8分的GERD症状改善。结论ASD患者中有39%被诊断为反流d。在这些患者中，69%的患者在矫正手术后6个月内胃食管反流症状得到改善，并维持至术后5年。这些幻灯片可以在电子补充材料中检索。
Purpose Gastroesophageal reflux disease (GERD) is reported as one of the symptoms of adult spinal deformity (ASD). Little is known about the mid- to long-term improvement in GERD symptoms after ASD surgery. Therefore, this retrospective study from prospectively collected database aimed to investigate GERD symptoms in patients for a minimum of 2 years after ASD corrective surgery. Methods Records from 230 patients (mean age: 64 years) who underwent ASD surgery were examined using the frequency scale for the symptoms of GERD (FSSG) questionnaires for the diagnosis of GERD. FSSG scores and radiographic parameters were investigated preoperatively and postoperatively at 6 months and 1, 2, and 5 years. Results In total, 90 (39%) patients were preoperatively diagnosed with GERD defined by FSSG score >= 8 points. Radiographic results showed that the corrective surgeries improved local and global alignments. In the GERD patients, preoperative FSSG scores (16.1 +/- 7.3 points) significantly improved to 7.7 +/- 7.4 points within 6 months postoperatively (p < 0.001), and postoperative FSSG scores maintained at 1 year (9.9 +/- 8.2 points, p = 0.061), 2 years (9.7 +/- 8.2 points, p = 0.086), and 5 years (9.4 +/- 8.0 points, p = 0.177). Among the GERD group, 62 patients (69%; improvement cases) showed improvement in GERD symptoms defined by FSSG score < 8 points within 6 months postoperatively. Conclusions Among ASD patients, 39% were diagnosed with GERD. In 69% of these patients, GERD symptoms improved within 6 months of corrective surgery and maintained up to 5 years postoperatively. Graphic abstract These slides can be retrieved under Electronic Supplementary Material.