Screening interval breast cancers: Mammographic features and prognostic factors
Screening interval breast cancers: Mammographic features and prognostic factors
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DOI:
10.1148/radiology.199.3.8638010
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发表时间:
1996-06-01
期刊:
影响因子:
19.7
通讯作者:
Robertson, JFR
中科院分区:
文献类型:
--
作者:
Burrell, HC;Sibbering, DM;Robertson, JFR
PURPOSE: To review the mammographic features of screening interval breast cancers and to compare the tumor size, histologic grade, and lymph node involvement with those in screening-detected and unscreened symptomatic cancers.MATERIALS AND METHODS: Screening mammography was performed in 72,773 women aged 50-64 years. Ninety interval cancers were identified in 89 women. The mammographic and histopathologic features of these cancers were analyzed.RESULTS: At review of the screening mammograms, interval cancers were classified into four groups: 51 true-positive, 20 false-negative, seven mammographically occult, and 12 unclassified. The most common missed abnormality in the false-negative cases was architectural distortion. Interval cancers were larger, of higher grade, and more likely to have lymph node involvement than screening-detected tumors and were of similar size, histologic grade, and stage of lymph node involvement as symptomatic tumors.CONCLUSION: Prognosis in interval cancers is similar to that in symptomatic, unscreened tumors and statistically significantly worse than that in screening-detected cancers.