Screening interval breast cancers: Mammographic features and prognostic factors

Screening interval breast cancers: Mammographic features and prognostic factors
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DOI:
10.1148/radiology.199.3.8638010
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发表时间:
1996-06-01
期刊:
影响因子:
19.7
通讯作者:
Robertson, JFR
Robertson, JFR
中科院分区:
医学1区
文献类型:
--
作者:
Burrell, HC;Sibbering, DM;Robertson, JFR

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目得:审查筛查间隔期乳腺癌的乳房X线摄影特征,并比较肿瘤大小,组织学分级和淋巴结受累与筛查检测和未筛查的症状cancer.MATERIALS和METHODS:筛查乳房X线摄影进行了72,773名妇女年龄在50-64岁。在89名妇女中发现了90例间隔癌。这些癌症的乳腺摄影和组织病理学特征进行了分析。结果:在审查的筛查乳腺X线照片,间隔癌症分为四组:51个真阳性,20个假阴性,7个乳腺摄影隐匿,和12个未分类。在假阴性病例中最常见的漏诊异常是结构变形。间隔癌症是更大的,更高的级别,更有可能有淋巴结的参与比筛选检测到的肿瘤和类似的大小,组织学分级,淋巴结的参与症状tumors.CONCLUSION阶段:在间隔癌症的预后是类似的症状,未筛选的肿瘤和统计学显着不如在筛选检测到的癌症。
PURPOSE: To review the mammographic features of screening interval breast cancers and to compare the tumor size, histologic grade, and lymph node involvement with those in screening-detected and unscreened symptomatic cancers.MATERIALS AND METHODS: Screening mammography was performed in 72,773 women aged 50-64 years. Ninety interval cancers were identified in 89 women. The mammographic and histopathologic features of these cancers were analyzed.RESULTS: At review of the screening mammograms, interval cancers were classified into four groups: 51 true-positive, 20 false-negative, seven mammographically occult, and 12 unclassified. The most common missed abnormality in the false-negative cases was architectural distortion. Interval cancers were larger, of higher grade, and more likely to have lymph node involvement than screening-detected tumors and were of similar size, histologic grade, and stage of lymph node involvement as symptomatic tumors.CONCLUSION: Prognosis in interval cancers is similar to that in symptomatic, unscreened tumors and statistically significantly worse than that in screening-detected cancers.