Results of a rubella screening program for hospital employees: a five-year review (1986-1990).
Results of a rubella screening program for hospital employees: a five-year review (1986-1990).
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医院员工风疹筛查计划的结果：五年回顾（1986-1990）。
DOI：
10.1093/oxfordjournals.aje.a116913
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发表时间：
1993
影响因子：
5
通讯作者：
Dunagan,WC
中科院分区：
文献类型：
--
作者：
Fraser,V;Spitznagel,E;Medoff,G;Dunagan,WC
在1986年1月1日至1990年12月31日的5年期间，对巴恩斯医院员工健康服务（圣路易斯，密苏里州）风疹筛查计划进行了评价。共有6 969名新雇员被雇用，6 115人（87.7%）接受了雇员保健服务的风疹免疫检查。对5，893名（96.4%）接受筛查的员工进行了风疹血清学检查，而222名（3.6%）有既往风疹疫苗接种或风疹感染的记录。在325名雇员中发现了免疫力缺失，占所有筛查人员的5.3%。女性比男性更频繁地接受雇员健康服务的筛查（p<0.0001），黑人比非西班牙裔白人更频繁地接受筛查（p<0.0001）。医生的筛查频率低于其他科室组（p<0.0001）。每年的血清阴性率从4.45%到6.76%不等，但这些差异并不显著。Logistic回归分析表明，5岁出生队列与血清学状态显着相关。1960-1964年出生的雇员最不可能是血清反应阴性，1970年或以后出生的雇员最有可能是血清反应阴性。性别，种族和部门组血清学状态的预测，虽然从不同的风疹检测结果的显着差异被检测到。只有13.8%的血清反应阴性的雇员随后通过雇员保健服务接种了疫苗。本研究证明血清阴性率低于既往研究。它确定了可能逃避风疹筛查和低疫苗接种率的雇员群体。它发现1964年以后出生的员工中血清阴性率的增加与美国风疹发病率的增加有关。
The Barnes Hospital Employee Health Service (St. Louis, Missouri) rubella screening program was evaluated over the 5-year period between January 1,1986, and December 31,1990. A total of 6,969 new employees were hired, and 6,115 (87.7%) were screened for evidence of rubella immunity by the Employee Health Service. Rubella serology was performed on 5,893 (96.4%) of the screened employees, while 222 (3.6%) had documentation of prior rubella vaccination or rubella infection. The absence of immunity was identified in 325 employees or 5.3% of all those screened. Women were more frequently screened by the Employee Health Service than were men (p<0.0001), and blacks were more frequently screened than were non-Hispanic Caucasians (p<0.0001). Physicians were less frequently screened than were other departmental groups (p<0.0001). The rate of seronegativity for each year of hire varied from 4.45 to 6.76%, but these differences were not significant. Logistic regression analysis demonstrated that 5-year birth cohorts correlated significantly with serologic status. Employees born in 1960–1964 were least likely to be seronegative, and employees born in 1970 or later were most likely to be seronegative. Sex, race, and department group were not predictive of serologic status, although significant differences in results from different rubella assays were detected. Only 13.8% of seronegative employees were subsequently vaccinated by the Employee Health Service. This study demonstrates a lower seronegativity rate than did previous studies. It identifies groups of employees likely to escape rubella screening and low vaccination rates. It finds increasing seronegativity among employees born after 1964 that correlates with the reported increasing rates of rubella in the United States.