Aptamer database
Aptamer database
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DOI：
10.1093/nar/gkh094
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发表时间：
2004-01-01
影响因子：
14.9
通讯作者：
Ellington, AD
中科院分区：
文献类型：
--
作者：
Lee, JF;Hesselberth, JR;Ellington, AD
适体数据库被设计成包含关于适体和非天然核酶的全面序列信息，所述非天然核酶已经通过体外选择方法产生。这样的数据通常不收集在“天然”序列数据库中，例如GenBank。除了作为一个可能具有诊断或治疗效用的序列库外，该数据库还为描述和探索适应性景观的理论生物学家提供了宝贵的资源。该数据库每月更新一次，可在http：//aptamer上公开查阅。icmb.utexas.edu/.
The aptamer database is designed to contain comprehensive sequence information on aptamers and unnatural ribozymes that have been generated by in vitro selection methods. Such data are not normally collected in 'natural' sequence databases, such as GenBank. Besides serving as a storehouse of sequences that may have diagnostic or therapeutic utility, the database serves as a valuable resource for theoretical biologists who describe and explore fitness landscapes. The database is updated monthly and is publicly available at http://aptamer. icmb.utexas.edu/.