Diffusion-weighted breast MRI: Clinical applications and emerging techniques.
Diffusion-weighted breast MRI: Clinical applications and emerging techniques.
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扩散加权乳房MRI：临床应用和新兴技术。
DOI：
10.1002/jmri.25479
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发表时间：
2017-02
期刊：
影响因子：
--
通讯作者：
Sigmund EE
中科院分区：
文献类型：
--
作者：
Partridge SC;Nissan N;Rahbar H;Kitsch AE;Sigmund EE
弥散加权MRI （DWI）具有提高乳腺癌检测和生物学特征的潜力。DWI越来越多地被纳入乳腺MRI方案，以解决常规临床乳腺MRI的一些缺点。潜在的好处包括改善乳腺良恶性病变的鉴别，评估和预测治疗效果，以及乳腺癌的非对比检测。乳房呈现出独特的成像环境，具有显著的生理和学科间变化，以及获得可靠的高质量扩散加权MR图像的特定挑战。技术创新正在帮助克服许多图像质量问题，这些问题限制了DWI在乳房成像中的广泛应用。先进的建模方法可以进一步表征组织灌注、复杂性和腺体组织，可以扩展知识并产生改进的诊断工具。
Diffusion weighted MRI (DWI) holds potential to improve the detection and biological characterization of breast cancer. DWI is increasingly being incorporated into breast MRI protocols to address some of the shortcomings of routine clinical breast MRI. Potential benefits include improved differentiation of benign and malignant breast lesions, assessment and prediction of therapeutic efficacy, and non-contrast detection of breast cancer. The breast presents a unique imaging environment with significant physiologic and inter-subject variations, as well as specific challenges to achieving reliable high quality diffusion weighted MR images. Technical innovations are helping to overcome many of the image quality issues that have limited widespread use of DWI for breast imaging. Advanced modeling approaches to further characterize tissue perfusion, complexity, and glandular organization may expand knowledge and yield improved diagnostic tools.