Lymphatic mapping with isosulfan blue dye in squamous cell carcinoma of the head and neck.
Lymphatic mapping with isosulfan blue dye in squamous cell carcinoma of the head and neck.
复制标题
使用异硫蓝染料在头颈部鳞状细胞癌中进行淋巴图谱分析。
DOI：
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发表时间：
1998
期刊：
影响因子：
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通讯作者：
E. Myers
中科院分区：
文献类型：
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作者：
K. Pitman;Jonas T. Johnson;H. Edington;E. Barnes;R. Day;R. Wagner;E. Myers
客观化
为了确定术中异硫氰蓝染色淋巴标测和前哨淋巴结活检是否能准确地显示头颈部鳞状细胞癌粘膜部位的区域转移途径。
设计
术中淋巴管标测的前瞻性临床研究。
设置
一个学术第三级转介中心。
病人
未经治疗的头颈部鳞状细胞癌患者，其外科治疗包括颈清扫术。
干预
在颈淋巴清扫术中，将异硫氰蓝染料注射到上呼吸道鳞状细胞癌周围的粘膜中。
结果衡量标准
蓝色前哨淋巴结的病理结果与其余颈部淋巴管的病理结果的相关性。
结果
在注射异硫丹染料的原发鳞状细胞癌周围的粘膜后，没有发现蓝色染色的颈部淋巴管。
结论
异硫氰蓝染色的术中淋巴标测技术需要进一步研究，才能用于检测头颈部鳞状细胞癌的隐匿性颈部转移。
OBJECTIVE
To determine whether intraoperative lymphatic mapping with isosulfan blue dye and sentinel lymph node biopsy accurately demonstrates the pathway of regional metastases from mucosal sites in squamous cell carcinoma of the head and neck.
DESIGN
A prospective clinical study of intraoperative lymphatic mapping.
SETTING
An academic tertiary referral center.
PATIENTS
Patients with previously untreated squamous cell carcinoma of the head and neck whose surgical treatment included neck dissection.
INTERVENTION
Injection of isosulfan blue dye into the mucosa surrounding squamous cell carcinomas of the upper aerodigestive tract during cervical lymphadenectomy.
OUTCOME MEASURES
Correlation of the pathologic findings in the blue sentinel lymph node with those in the remaining cervical lymphatics.
RESULTS
No blue-stained cervical lymphatics were identified after injection of the mucosa surrounding the primary squamous cell carcinoma with isosulfan dye.
CONCLUSION
The technique of intraoperative lymphatic mapping with isosulfan blue dye requires further study before it can be used for the detection of occult cervical metastases in squamous cell carcinoma of the head and neck.
影响因子：
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作者：
D. Morton;Wenger Dr;J. Wong;J. Economou;L. Cagle;Storm Fk;L. Foshag;A. Cochran
通讯作者：
D. Morton;Wenger Dr;J. Wong;J. Economou;L. Cagle;Storm Fk;L. Foshag;A. Cochran