Mood disorders in opioid-dependent patients
Mood disorders in opioid-dependent patients
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DOI：
10.1016/j.jad.2003.09.015
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发表时间：
2004-10-01
影响因子：
6.6
通讯作者：
Mohagheghzadeh, M
中科院分区：
文献类型：
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作者：
Ahmadi, J;Majdi, B;Mohagheghzadeh, M
目的：评估阿片类药物依赖门诊患者当前情绪障碍的发生率。设计：DSM-IV心境障碍的患病率研究。设置：私人和政府诊所。参与者：500名自愿寻求治疗的无偿阿片类药物依赖患者。测量：DSM-IV轴I障碍（SCID-I）的结构化临床访谈的研究版本。结果：受试者（487名男性和13名女性）的平均年龄为33.4岁，范围从16岁到67岁。大多数人（68.2%）在私营部门工作，13.4%失业。大多数人（59.8%）受过小学、辅导或高中教育，只有3.8%是文盲。336名（67.2%）受试者被诊断为情绪障碍。在受试者中，274人（54.8%）患有物质诱发的抑郁症，37人（7.4%）患有重度抑郁症，14人（2.8%）患有心境恶劣，5人（1%）因一般医疗状况而患抑郁症，3人（0.6%）患有心境恶劣，3人（0.6%）患有双相情感障碍I型。没有人被诊断为双相情感障碍II型。在参与者中，319人（63.8%）报告使用阿片类药物超过5年。在受试者中，仅16例（3.2%）未报告禁欲发作，大多数484例（96.8%）报告了一次或多次禁欲发作。约4.2%（21例）报告的阿片类药物使用量低于1 g/天，大多数86.4%（432例）报告的阿片类药物使用量在1 - 5 g/天之间。结论：由于阿片类药物依赖受试者的情绪障碍发生率很高，精神科服务应向患者开放并可获得，特别是那些自愿寻求帮助和治疗的患者。(C)2003 Elsevier B. V.保留所有权利。
Aims: To assess the rate of current mood disorders in opioid-dependent outpatients. Design: Prevalence study of DSM-IV mood disorders. Settings: Private and government clinics. Participants: Five hundred unpaid opioid-dependent patients who had voluntarily sought treatment. Measurements: The Research version of structured clinical interview for DSM-IV Axis I Disorders (SCID-I). Results: The mean age of the subjects (487 men and 13 women) was 33.4 years, ranging from 16 to 67. The majority (68.2%) had private sector job and 13.4% were unemployed. The majority (59.8%) had education at the level of primary, guidance or high school and only 3.8% were illiterate. Three hundred and thirty six (67.2%) subjects were diagnosed as having mood disorders. Of the subjects 274 (54.8%) had substance induced depression, 37 (7.4%) major depression, 14 (2.8%) dysthymia, five (1%) depression due to general medical condition, three (0.6%) cylothymia, three (0.6%) bipolar mood disorder type I. None was diagnosed as having bipolar mood disorder type II. Of the participants 319 (63.8%) reported more than 5 years use of opioid. Of the subjects only 16 (3.2%) reported no episode of abstinence and the majority 484 (96.8%) reported one or more episodes of abstinences. About 4.2% (21) reported less than 1 g/day and the majority 86.4% (432) reported between 1 and 5 g/day current use of opioid. Conclusion: Due to high rates of mood disorders in opioid-dependent subjects, psychiatric services should be open and accessible to the patients, especially those who voluntarily seek help and treatment. (C) 2003 Elsevier B.V. All rights reserved.