A qualitative comparison of protein synthesis in the preimplantation embryos of four rodent species (mouse, rat, hamster, gerbil)
A qualitative comparison of protein synthesis in the preimplantation embryos of four rodent species (mouse, rat, hamster, gerbil)
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四种啮齿类动物（小鼠、大鼠、仓鼠、沙鼠）植入前胚胎蛋白质合成的定性比较
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发表时间：
1985
期刊：
影响因子：
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通讯作者：
M. Surani
中科院分区：
文献类型：
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作者：
M. Norris;S. Barton;M. Surani
对小鼠、大鼠、仓鼠和沙土鼠着床前胚胎蛋白质谱的检测表明，单细胞受精卵存在显著的物种差异，但胚泡产生的主要蛋白质具有显著的相似性。在所有四个物种中观察到的蛋白质图谱的早期变化表明，在第二次卵裂分裂之前激活胚胎基因组是啮齿类动物的特征。由假定的母体转录本产生的最初标记的物种差异对于建立和维持物种完整性可能是重要的。
An examination of the protein profiles obtained from preimplantation embryos of mouse, rat, hamster, and gerbil revealed marked species differences in the one-cell fertilized eggs but a striking similarity in the major proteins produced by blastocysts. The early change in protein profile observed in all four species suggests that activation of the embryonic genome before the second cleavage division is a rodent characteristic. The initial marked species differences resulting from putative maternal transcripts could be important in the establishment and maintenance of species integrity.