Research applications of magnetic resonance spectroscopy to investigate psychiatric disorders.
Research applications of magnetic resonance spectroscopy to investigate psychiatric disorders.
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DOI：
10.1097/rmr.0b013e318181e0be
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发表时间：
2008-04-01
期刊：
影响因子：
--
通讯作者：
Posse, Stefan
中科院分区：
文献类型：
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作者：
Dager, Stephen R;Corrigan, Neva M;Posse, Stefan
磁共振波谱(MRS)方法和相关分析策略的进步使对精神障碍疾病病理的神经生物学模型进行了复杂的测试。概述了MRS的基本原则、方法学考虑和调查方法。对最近的研究进行了综述，重点介绍了应用MRS，特别是氢MRS，系统地研究特定的精神疾病的创新方法，包括自闭症谱系障碍、精神分裂症、惊恐障碍、严重抑郁症和双相情感障碍。
Advances in magnetic resonance spectroscopy (MRS) methodology and related analytic strategies allow sophisticated testing of neurobiological models of disease pathology in psychiatric disorders. An overview of principles underlying MRS, methodological considerations, and investigative approaches is presented. A review of recent research is presented that highlights innovative approaches applying MRS, in particular, hydrogen MRS, to systematically investigate specific psychiatric disorders, including autism spectrum disorders, schizophrenia, panic disorder, major depression, and bipolar disorder.