Temperature sensitivity of the passive outflow of 5-hydroxytryptamine from blood platelets.

Temperature sensitivity of the passive outflow of 5-hydroxytryptamine from blood platelets.
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5-羟色胺从血小板被动流出的温度敏感性。

DOI:
10.1016/0024-3205(65)90239-0
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发表时间:
1965
期刊:
影响因子:
6.1
通讯作者:
G. Bartholini
G. Bartholini
中科院分区:
医学2区
文献类型:
--
作者:
M. da Prada;A. Pletscher;G. Bartholini

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本文研究了在不同实验条件下,无糖磷酸二氢钾溶液、含KCN或Ro_4-6861的血浆及含KCN或Ro_4-6861的血浆中、CH3HgI预孵育的血小板以及外源性5-羟色胺保存的血小板中,温度对5-羟色胺被动流出的影响。有明显的温度依赖性,特别是在30°C到40°C之间。
The effect of temperature on the passive outflow of 5HT from isolated blood platelets of rabbits has been investigated under various experimental conditions, i.e. in glucose-free K-phosphate, in Tyrode solution and plasma supplemented with KCN or Ro 4-6861, in platelets preincubated with CH3HgI, as well as in reserpinized platelets loaded with exogenous 5HT. A marked temperature dependence could be demonstrated especially between 30° and 40°C.