A randomized trial of intensive outpatient (IOP) vs. standard outpatient (OP) buprenorphine treatment for African Americans.
A randomized trial of intensive outpatient (IOP) vs. standard outpatient (OP) buprenorphine treatment for African Americans.
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DOI:
10.1016/j.drugalcdep.2012.08.027
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发表时间:
2013-03-01
影响因子:
4.2
通讯作者:
Jaffe, Jerome H.
中科院分区:
文献类型:
--
作者:
Mitchell, Shannon Gwin;Gryczynski, Jan;Schwartz, Robert P.;O'Grady, Kevin E.;Olsen, Yngvild K.;Jaffe, Jerome H.
Buprenorphine is increasingly being used in community-based treatment programs, but little is known about the optimal level of psychosocial counseling in these settings. The aim of this study was to compare the effectiveness of OP and IOP level counseling when provided as part of buprenorphine treatment for opioid-dependent African Americans. Participants were African American men and women starting buprenorphine treatment at one of two community-based clinics (N=300). Participants were randomly assigned to OP or IOP. Measures at baseline, 3- and 6-months included the primary outcome of DSM-IV opioid and cocaine dependence criteria, as well as additional outcomes of illicit opioid and cocaine use (urine test and self-report), criminal activity, retention in treatment, Quality of Life, Addiction Severity Index composite scores, and HIV risk behaviors. Participants assigned to OP received, on average, 3.67 (SD=1.30) hours of counseling per active week in treatment. IOP participants received an average of 5.23 (SD=1.68) hours of counseling per active week (less than the anticipated 9 hours per week of counseling). Both groups showed substantial improvement over a 6-month period on nearly all measures considered. There were no significant differences between groups in meeting diagnostic criteria for opioid (p=.67) or cocaine dependence (p=.63). There were no significant between group differences on any of the other outcomes. A secondary analysis restricting the sample to participants meeting DSM-IV criteria for baseline cocaine dependence also revealed no significant between-group differences (all ps>.05). Buprenorphine patients receiving OP and IOP levels of care both show short-term improvements.
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DOI:
10.1111/j.1360-0443.2011.03700.x
发表时间:
2012-05
期刊:
Addiction (Abingdon, England)
影响因子:
--
作者:
Schwartz RP;Kelly SM;O'Grady KE;Gandhi D;Jaffe JH
通讯作者:
Jaffe JH
影响因子:
3.9
作者:
Forman, RF;Svikis, D;Blaine, J
通讯作者:
Blaine, J
影响因子:
2.8
作者:
Reisinger HS;Schwartz RP;Mitchell SG;Peterson JA;Kelly SM;O'Grady KE;Marrari EA;Brown BS;Agar MH
通讯作者:
Agar MH
影响因子:
3.8
作者:
Gottheil, E;Weinstein, SP;Serota, RD
通讯作者:
Serota, RD
影响因子:
3.9
作者:
Schwartz RP;Kelly SM;O'Grady KE;Gandhi D;Jaffe JH
通讯作者:
Jaffe JH