A pilot study of concordance therapy for individuals with bipolar disorders who are non-adherent with lithium prophylaxis
A pilot study of concordance therapy for individuals with bipolar disorders who are non-adherent with lithium prophylaxis
复制标题
DOI：
10.1034/j.1399-5618.2002.02242.x
复制
发表时间：
2002-12-01
影响因子：
5.4
通讯作者：
Tacchi, MJ
中科院分区：
文献类型：
--
作者：
Scott, J;Tacchi, MJ
目的：为了评估一致性治疗（CCT）的可接受性和可行性，以提高遵守锂预防在个人双相disorder.Methods：10例双相I型障碍和自我报告的锂坚持问题被招募。其中8人参加了由认知疗法专家提供的为期6个月的CCT研究。在干预前和干预后，对自我报告的锂依从性、对锂的态度和知识以及血清锂水平进行了可靠和有效的评估。受试者的CCT的意见也recorded.Results：统计学显着改善锂（平均得分基线= 6.8;后续= 4.1;效果大小= 1.6）的态度与自我报告的依从性的改善。实验室结果显示，血清血浆锂水平在统计学上显著升高（平均值从0.41升高至0.6;效应量1.7）。受试者认为CCT是可接受的干预措施。然而，只有4的10个科目完成了所有7个半小时的治疗会议和家庭作业Tasks.Conclusions：这个小的开放式研究表明，CCT可能是一个有用的除了“阶梯式护理”治疗的个人双相情感障碍。目前正在进行研究，以评估其疗效，并确定新手治疗师是否也可以有效地应用该模型。
Objectives: To assess the acceptability and feasibility of concordance therapy (CCT) in improving adherence with lithium prophylaxis in individuals with bipolar disorder.Methods: Ten subjects with bipolar I disorder and self-reported problems with lithium adherence were recruited. Eight participated in a 6-month study of CCT delivered by a expert in cognitive therapy. Reliable and valid assessments of self-reported adherence with lithium, attitudes towards, and knowledge of lithium and serum plasma lithium levels were measured pre- and post-intervention. Subjects views of CCT were also recorded.Results: Statistically significant improvements in attitudes towards lithium ( mean score baseline = 6.8; follow up = 4.1; Effect size = 1.6) were associated with improvements in self-reported adherence. Laboratory results demonstrated statistically significant increases in serum plasma lithium levels ( mean increased from 0.41 to 0.6; effect size 1.7). Subjects viewed CCT as an acceptable intervention. However, only four of the 10 subjects completed all seven half-hour therapy sessions and homework tasks.Conclusions: This small ope study suggests that CCT may represent a useful addition to the 'stepped care' package of treatment for individuals with bipolar disorders. Research is underway to assess its efficacy and to establish whether novice therapists can also apply the model effectively.