Characterization and biological activity of essential oils from fruits of Zanthoxylum xanthoxyloides Lam. and Z. leprieurii Guill. & Perr., two culinary plants from Cameroon
Characterization and biological activity of essential oils from fruits of Zanthoxylum xanthoxyloides Lam. and Z. leprieurii Guill. & Perr., two culinary plants from Cameroon
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DOI：
10.1002/ffj.3083
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发表时间：
2012-03-01
影响因子：
2.6
通讯作者：
Barboni, Luciano
中科院分区：
文献类型：
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作者：
Fogang, Hervet P. D.;Tapondjou, Leon A.;Barboni, Luciano
花椒和花椒干果实经水蒸气蒸馏得到的挥发油。采用气相色谱-火焰离子化检测器和气相色谱-质谱联用技术对芸香科植物leprieurii的化学成分进行了分析。前者的主要挥发性成分为香茅醇（29.9%）和香叶醇（11.5%），其次为乙酸香茅酯（5.5%）、柠檬烯（5.5%）和香茅醛（4.6%），后者的主要成分分别为（E）-β-罗勒烯（29.4%）、月桂烯（28.6%）、柠檬烯（13.6%）和α-蒎烯（8.1%）。化学成分支持这些植物在当地食物中作为香料的传统用途。分别采用MTT法、琼脂扩散法、DPPH法、ABTS法和β-胡萝卜素油酸法测定其抗增殖、抗菌和抗氧化活性。Z. xanthoxyloides可能与香叶醇和香茅醇的存在有关，香叶醇和香茅醇对所有测试的人类肿瘤细胞系表现出强的抗增殖活性，并支持该植物用于治疗各种癌症的当地传统用途。版权所有（c）2012约翰威利父子有限公司
Essential oils obtained by hydrodistillation of dried fruits of Zanthoxylum xanthoxyloides and Z. leprieurii (Rutaceae), were analysed by gas chromagraphyflame ionization detection and gas chromatographymass spectrometry. In the former, the major volatiles resulted citronellol (29.9%) and geraniol (11.5%), followed by citronellyl acetate (5.5%), limonene (5.5%) and citronellal (4.6%), while in the latter the major compounds were (E)-beta-ocimene (29.4%), myrcene (28.6%), limonene (13.6%) and a-pinene (8.1%), respectively. The chemical composition supports the traditional use of these plants as spices in local food. The oils were also tested for antiproliferative, antimicrobial and antioxidant activities by MTT assay, agar disc diffusion method, and DPPH, ABTS and beta-carotenelinoleic acid assay, respectively. The noteworthy cytotoxic effects of Z. xanthoxyloides are probably related to the presence of geraniol and citronellol, which exhibited strong antiproliferative activity against all the tested human tumor cell lines, and support the local traditional use of this plant for the treatment of various cancers. Copyright (c) 2012 John Wiley & Sons, Ltd.