Six New Sesquiterpenes from Eupatorium lindleyanum
Six New Sesquiterpenes from Eupatorium lindleyanum
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DOI：
10.1002/hlca.201200083
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发表时间：
2012-09
影响因子：
1.8
通讯作者：
Shuangqing Wu;Nai-yu Xu;Qun Sun;Hai-Yan Han;Jian Zhang
中科院分区：
文献类型：
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作者：
Shuangqing Wu;Nai-yu Xu;Qun Sun;Hai-Yan Han;Jian Zhang
从野马追（Eupatorium lindleyanum DC.）的氯仿提取物中分离得到6个新的吉马烷型倍半萜内酯1-6。这些化合物的结构通过光谱分析确定，包括1D-和2D-NMR光谱的解释。测试化合物1-6对NB 4和K562白血病细胞系的细胞毒性，显示化合物2和5具有有效的细胞毒性（表3）。
The six new germacrane-type sesquiterpenoid lactones 1–6 were isolated from the CHCl3 extract of Eupatorium lindleyanum DC. The structures of these compounds were determined by spectroscopic analyses, including interpretation of 1D- and 2D-NMR spectra. Compounds 1–6 were tested for cytotoxicity against NB4 and K562 leukemia cell lines, showing that 2 and 5 possess potent cytotoxicity (Table 3).