RNAi methods for management of insects and their pathogens.
RNAi methods for management of insects and their pathogens.
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DOI：
10.1079/pavsnnr20127004
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发表时间：
2012-01-01
期刊：
影响因子：
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通讯作者：
Palli, S. R.
中科院分区：
文献类型：
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作者：
Palli, S. R.
RNA干扰（RNAi）是1998年发现的一种转录后基因沉默方法，已被用于几乎所有生物学领域的基础研究，以沉默基因，以了解其功能。这项技术在分子医学、农业和许多其他领域也有许多潜在的应用。RNAi已被广泛用于了解昆虫生理、发育、行为和生殖过程的分子基础。这项技术也有可能协助制定针对害虫和病原体的有针对性的管理方法，这些害虫和病原体会引起益虫的疾病。本文综述了RNAi技术及其在防治害虫和益虫病原体中的应用。
RNA interference (RNAi), a post-transcriptional gene silencing method discovered in 1998, has been used in basic research in almost every area of biology to silence genes in order to learn about their function. This technology also has many potential applications in molecular medicine, in agriculture and many other fields. RNAi has been extensively used to understand the molecular basis of physiological, developmental, behavioural and reproductive processes in insects. This technology also has a potential to assist in developing target-specific management methods for insect pests and pathogens that cause diseases in beneficial insects. Recent literature on RNAi methods and their applications for controlling insect pests and pathogens that cause diseases in beneficial insects will be reviewed.