Highly efficient biocatalysts via covalent immobilization of Candida rugosa lipase on ethylene glycol-modified gold-silica nanocomposites

Highly efficient biocatalysts via covalent immobilization of Candida rugosa lipase on ethylene glycol-modified gold-silica nanocomposites
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DOI:
10.1002/adma.200306022
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发表时间:
2004-02-03
期刊:
影响因子:
29.4
通讯作者:
Rotello, VM
Rotello, VM
中科院分区:
材料科学1区
文献类型:
--
作者:
Drechsler, U;Fischer, NO;Rotello, VM

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二氧化硅和金纳米颗粒的聚合物介导的自组装(参见图和封面中的插图)导致延伸的聚集体。在煅烧和随后的表面改性后,这些聚集体用作脂肪酶共价固定化的载体(参见方案)。所得生物催化剂表现出高效率和长期稳定性。
The polymer-mediated self-assembly of silica and gold nanoparticles (see inset in Figure and cover) leads to extended aggregates. After calcination and subsequent surface modification, these aggregates serve as supports for the covalent immobilization of lipase (see Scheme). The obtained biocatalysts exhibit high efficiencies and long-term stability.