Usefulness of sputum culture for diagnosis of bacterial pneumonia in HIV-infected patients
Usefulness of sputum culture for diagnosis of bacterial pneumonia in HIV-infected patients
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DOI：
10.1007/s10096-002-0729-x
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发表时间：
2002-05-01
影响因子：
4.5
通讯作者：
Nuño, E
中科院分区：
文献类型：
--
作者：
Cordero, E;Pachón, J;Nuño, E
在免疫功能正常的社区获得性肺炎患者中使用痰培养存在争议。这项技术对艾滋病毒感染者的有用性尚未得到评估。一项前瞻性、观察性、多中心、以医院为基础的细菌性社区获得性肺炎研究，分析hiv感染患者痰培养的价值。只培养高质量的痰样本。总共包括355例细菌性社区获得性肺炎。病因诊断190例（53.5%）。痰液培养313例（88.1%），诊断性108例（34.5%）；痰液培养27例（96.3%）中，无菌检出的微生物与无菌检出的微生物相同。8例（87.5%）痰液和支气管镜培养均阳性的病例中，有7例的微生物学检查结果一致。这些结果表明，痰培养是一种有用的技术，因为它的可用性和易于操作，并且与无菌样品的培养有良好的相关性。
The use of sputum culture in immunocompetent patients with community-acquired pneumonia is controversial. The usefulness of this technique in HIV-infected patients has not been evaluated. A prospective, observational, multicenter, hospital-based study of bacterial community-acquired pneumonia was carried out to analyze the value of sputum culture in HIV-infected patients. Only good-quality sputum samples were cultured. Altogether, 355 cases of bacterial community-acquired pneumonia were included. An etiological diagnosis was obtained in 190 (53.5%) cases. Sputum was cultured in 313 (88.1%) cases, being diagnostic in 108 (34.5%), The microorganism identified in sputum culture was the same as that identified in sterile samples in 26 of 27 (96.3%) cases in which both cultures were diagnostic. The microbiologic Findings in sputum and bronchoscopic cultures were concordant in seven of eight (87.5%) cases in which both were positive. These results suggest that sputum culture is a useful technique, given its availability and ease of performance and its good correlation with culture of sterile samples.