The Concept of field cancerization
The Concept of field cancerization
复制标题
野癌化的概念
DOI：
10.1097/01.cmr.0000382771.75569.e1
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发表时间：
2010
影响因子：
2.2
通讯作者：
R. Kaufmann
中科院分区：
文献类型：
--
作者：
R. Kaufmann
到目前为止，黑色素瘤一直逃脱了针对晚期疾病的系统疗法的国际探索。成功的大剂量干扰素α-2b辅助治疗黑色素瘤，还没有被任何替代方案的药物，单独或联合。这一经验使我们能够得出与黑色素瘤的主动特异性免疫疗法有关的原则--特别是：
Melanoma has eluded international explorations of systemic therapeutics for advanced disease, to date. The successful adjuvant therapy of melanoma with IFN alfa-2b at high dosages, has not been surpassed by any alternative regimens of agents, alone or in combination. This experience allows us to draw principles that pertain to active specific immunotherapy of melanoma—particularly that: