Dynamics of magnetization in hyperpolarized gas MRI of the lung

Dynamics of magnetization in hyperpolarized gas MRI of the lung
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DOI:
10.1002/mrm.1910380111
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发表时间:
1997-07-01
影响因子:
3.3
通讯作者:
Swartz, J
Swartz, J
中科院分区:
医学3区
文献类型:
--
作者:
Johnson, GA;Cates, G;Swartz, J

文献摘要

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超极化气体(HP)MRI中的磁化是由激光极化产生的,与磁体和成像过程无关。因此,在图像采集期间不存在平衡磁化。气体流入和自旋去极化的竞争过程导致信号在一个样本k空间中的大的变化。建立了在肺的输注和体内成像期间超极化He-3的极化的动态变化的模型,并且在活豚鼠中进行了实验验证,投影编码用于测量随时间分辨率的视点间变化
The magnetization in hyperpolarized gas (HP) MRI is generated by laser polarization that is independent of the magnet and imaging process. As a consequence, there is no equilibrium magnetization during the image acquisition, The competing processes of gas inflow and depolarization of the spins lead to large changes in signal as one samples k-space, A model is developed of dynamic changes in polarization of hyperpolarized He-3 during infusion and in vivo imaging of the lung and verified experimentally in a live guinea pig, Projection encoding is used to measure the view-to-view variation with temporal resolution