Increase in pruritogenic kallikrein 5 in the skin of NC mice with chronic dermatitis
Increase in pruritogenic kallikrein 5 in the skin of NC mice with chronic dermatitis
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DOI：
10.1111/exd.12828
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发表时间：
2015-12-01
影响因子：
3.6
通讯作者：
Kuraishi, Yasushi
中科院分区：
文献类型：
--
作者：
Andoh, Tsugunobu;Tsujii, Kenichiro;Kuraishi, Yasushi
这篇文章讨论了一项研究，该研究考察了激肽释放酶(KLK)5是否会对患有特应性皮炎样瘙痒的小鼠产生瘙痒。内容包括KLK5活性的测量，皮内注射KLK5引起的注射部位的后爪抓挠，以及KLK5在小鼠皮肤中酶活性的增加。
The article discusses a study which examined whether kallikrein (KLK) 5 would be pruritogenic in mice with atopic dermatitis-like pruritus. Topics covered include the measurement of the activity of KLK5, the hind-paw scratching of the injection site elicited by those treated with an intradermal injection of KLK5 and the increase in the enzyme activity of KLK5 in the skin of mice.