Prediction of intra-abdominal and subcutaneous abdominal adipose tissue in healthy pre-pubertal children
Prediction of intra-abdominal and subcutaneous abdominal adipose tissue in healthy pre-pubertal children
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DOI：
10.1038/sj.ijo.0800624
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发表时间：
1998-06-01
影响因子：
4.9
通讯作者：
Nagy, TR
中科院分区：
文献类型：
--
作者：
Goran, MI;Gower, BA;Nagy, TR
目的：目的：探讨儿童腹内脂肪组织（IAAT）和腹部皮下脂肪组织（SAAT）与身体成分和人体测量学的关系，设计：横断面数据分析，对象：113名健康的白种人和非裔美国人，青春期前4- 10岁的儿童，测量：脐部水平的单层CT测量IAAT和SAAT;通过双能X线吸收法（DEXA）测量总脂肪和躯干脂肪;通过皮褶和周长进行人体测量评价。IAAT与腹部皮褶厚度相关性最强SAAT与DEXA躯干脂肪（r = 0.96）、DEXA总脂肪（r = 0.93）、腰围（r = 0.93）的相关系数分别为0.88、0.87。在逐步回归分析中，DEXA躯干脂肪、DEXA总脂肪和腹部皮褶厚度最能预测IAAT（R-2 = 0.85）; DEXA躯干脂肪、体重、腰围和腹部皮褶厚度最能预测SAAT（R-2 = 0.96）。在没有DEXA数据的情况下，IAAT最好通过腹部皮褶厚度、种族和肩胛下皮褶厚度进行预测（R-2 = 0.82），SAAT最好通过腰围、肩胛下皮褶厚度、身高和腹部皮褶厚度进行预测（R-2 = 0.92）。预测方程与DEXA和没有成功的交叉验证，在一个独立的样本中的12个额外的措施IAAT和SAAT.CONCLUSION：这些数据提供了有用的信息，可以帮助解释人体测量数据方面的体脂分布。IAAT和SAAT可以准确地估计在高加索和非洲裔美国人青春期前儿童从人体测量与DEXA数据的可用性。
OBJECTIVE: To examine the relationship of intra-abdominal adipose tissue (IAAT) and subcutaneous abdominal adipose tissue (SAAT) with body composition and anthropometry in children.DESIGN: Cross-sectional data analysis.SUBJECTS: 113 heathy Caucasian and African-American, pre-pubertal children aged 4-10y.MEASUREMENTS: IAAT and SAAT by single slice computed tomography at the level of the umbilicus; total fat and trunk fat by dual energy X-ray absorptiometry (DEXA); anthropometric evaluation by skinfolds and circumferences.RESULTS: IAAT was most strongly correlated with abdominal skinfold (r = 0.88) and trunk fat by DEXA (r = 0.87), and SAAT with trunk fat by DEXA (r = 0.96), total fat by DEXA (r = 0.93) and waist circumference (r = 0.93). In stepwise regression, IAAT was best predicted by trunk fat from DEXA, total fat from DEXA, and abdominal skinfold (R-2 = 0.85); SAAT was best predicted by trunk fat from DEXA, body weight, waist circumference and abdominal skinfold (R-2 = 0.96). In the absence of DEXA data, IAAT was best predicted by abdominal skinfold, ethnicity and subscapular skinfold (R-2 = 0.82) and SAAT was best predicted by waist circumference subscapular skinfold, height and abdominal skinfold (R-2 = 0.92). The prediction equations with and without DEXA were successfully cross-validated in an independent sample of 12 additional measures of IAAT and SAAT.CONCLUSION: These data provide useful information that can help in the interpretation of anthropometric data with regard to body fat distribution. IAAT and SAAT can be accurately estimated in Caucasian and African-American prepubertal children from anthropometry with and without the availability of DEXA data.