Occupation, Worker Vulnerability, and COVID-19 Vaccination Uptake: Analysis of the Virus Watch prospective cohort study.

Occupation, Worker Vulnerability, and COVID-19 Vaccination Uptake: Analysis of the Virus Watch prospective cohort study.
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DOI:
10.1016/j.vaccine.2022.10.080
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发表时间:
2022-12-12
期刊:
影响因子:
5.5
通讯作者:
Virus Watch Collaborative
Virus Watch Collaborative
中科院分区:
医学3区
文献类型:
--
作者:
Beale S;Burns R;Braithwaite I;Byrne T;Lam Erica Fong W;Fragaszy E;Geismar C;Hoskins S;Kovar J;Navaratnam AMD;Nguyen V;Patel P;Yavlinsky A;Van Tongeren M;Aldridge RW;Hayward A;Virus Watch Collaborative

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COVID-19疫苗接种的职业差异可能会影响疫苗接种计划的有效性,并为弱势工人和工作场所高暴露者带来特别风险。本研究旨在调查按职业(包括弱势群体)和职业暴露状况划分的COVID-19疫苗接种情况。我们使用了受雇或自雇成年人的数据,这些成年人提供了职业信息,作为病毒观察前瞻性队列研究的一部分(n = 19,595),并将其与研究获得的关于工作能力相关特征(年龄,医疗条件,肥胖状况)和基于工作暴露矩阵的工作相关COVID-19暴露的信息联系起来。根据与国家记录和研究记录的联系,获得任何COVID-19疫苗第一剂、第二剂和第三剂的受试者接种状态。我们按职业总体、能力相关特征和工作暴露计算了疫苗接种的比例和Sison-Glaz多项式95%置信区间。各职业的疫苗接种率第一剂为89-96%,第二剂为87-94%,第三剂为75-86%,运输、贸易、服务和销售人员的接种率一直最低。与非脆弱工人相比,脆弱工人在摄取方面的职业间差异往往较少,尽管临床脆弱的运输工人(各剂量为76%-89%)的摄取率低于其他几个职业群体(各剂量最大值为86%-96%)。SARS-CoV-2暴露风险低的工人的疫苗接种率(各剂量为86%-96%)高于风险升高或高的工人(各剂量为81%-94%)。不同职业的疫苗接种率差异,特别是在脆弱和高度暴露的工人中,可能会加剧感染结果中的职业和相关社会经济不平等。需要进一步调查影响差异摄取的职业和非职业因素,以便为未来COVID-19加强剂推广和类似疫苗接种计划提供相关干预措施。
Occupational disparities in COVID-19 vaccine uptake can impact the effectiveness of vaccination programmes and introduce particular risk for vulnerable workers and those with high workplace exposure. This study aimed to investigate COVID-19 vaccine uptake by occupation, including for vulnerable groups and by occupational exposure status. We used data from employed or self-employed adults who provided occupational information as part of the Virus Watch prospective cohort study (n = 19,595) and linked this to study-obtained information about vulnerability-relevant characteristics (age, medical conditions, obesity status) and work-related COVID-19 exposure based on the Job Exposure Matrix. Participant vaccination status for the first, second, and third dose of any COVID-19 vaccine was obtained based on linkage to national records and study records. We calculated proportions and Sison-Glaz multinomial 95% confidence intervals for vaccine uptake by occupation overall, by vulnerability-relevant characteristics, and by job exposure. Vaccination uptake across occupations ranged from 89-96% for the first dose, 87–94% for the second dose, and 75–86% for the third dose, with transport, trade, service and sales workers persistently demonstrating the lowest uptake. Vulnerable workers tended to demonstrate fewer between-occupational differences in uptake than non-vulnerable workers, although clinically vulnerable transport workers (76%-89% across doses) had lower uptake than several other occupational groups (maximum across doses 86%–96%). Workers with low SARS-CoV-2 exposure risk had higher vaccine uptake (86%-96% across doses) than those with elevated or high risk (81–94% across doses). Differential vaccination uptake by occupation, particularly amongst vulnerable and highly-exposed workers, is likely to worsen occupational and related socioeconomic inequalities in infection outcomes. Further investigation into occupational and non-occupational factors influencing differential uptake is required to inform relevant interventions for future COVID-19 booster rollouts and similar vaccination programmes.
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