Unilateral clustered papules on the palm

Unilateral clustered papules on the palm
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DOI:
10.1002/jvc2.234
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发表时间:
2023-12-01
期刊:
JEADV CLINICAL PRACTICE
影响因子:
--
通讯作者:
Liu,Ling
Liu,Ling
中科院分区:
其他
文献类型:
--
作者:
Pi,Yuhao;Liu,Ling

文献摘要

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1907年,Pinkus首次描述并命名了地衣。1 LN的发病机制尚不清楚,可能与感染或其他自身免疫性疾病有关。LN常见于儿童和青少年,没有明显的性别或种族差异。典型的临床表现是数量不等的散在的坚硬、有光泽、圆形或扁平的丘疹,这些丘疹保持离散,直径约为1-3 mm。LN倾向于发生在四肢、腹部、胸壁和阴茎。典型的病理改变为乳头增宽,局灶性、致密的炎性细胞呈球形浸润,形成“爪抓球”征。LN有几种亚型,包括局限性、全身性、光化性、囊泡性、穿孔性、出血性、紫癜性、角化病和线性。
DISCUSSIONLichen nitidus was first described and named by Pinkus in 1907. 1 The pathogenic mechanism of LN is still unclear and may be related to infection or other autoimmune diseases. LN is common in children and adolescents, with no apparent gender or racial differences. The typical clinical presentation is a variable number of scattered firm, shiny, round or flat papules, that remain discrete and measure approximately 1–3 mm in diameter. LN tends to occur on the extremities, abdomen, chest wall, and penis. Typical pathologic changes are papillary widening and focal, dense infiltration of inflammatory cells in a spherical shape, forming the “claw clutching ball” sign. There are several subtypes of LN, including limited, generalised, actinic, vesicular, perforating, hemorrhagic, purpuric, keratoderma, and linear.