Controversies in preterm brain injury.

Controversies in preterm brain injury.
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DOI:
10.1016/j.nbd.2015.10.012
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发表时间:
2016-08
影响因子:
6.1
通讯作者:
Gallo V
Gallo V
中科院分区:
医学1区
文献类型:
--
作者:
Penn AA;Gressens P;Fleiss B;Back SA;Gallo V

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In this review, we highlight critical unresolved questions in the etiology and mechanisms causing preterm brain injury. Involvement of neurons, glia, endogenous factors and exogenous exposures is considered. The structural and functional correlates of interrupted development and injury in the premature brain are under active investigation, with the hope that the cellular and molecular mechanisms underlying developmental abnormalities in the human preterm brain can be understood, prevented or repaired.