High-resolution anal manometry: Repeatability, validation, and comparison with conventional manometry
High-resolution anal manometry: Repeatability, validation, and comparison with conventional manometry
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DOI：
10.1111/nmo.13591
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发表时间：
2019-06-01
影响因子：
3.5
通讯作者：
Emmanuel, Anton, V
中科院分区：
文献类型：
--
作者：
Gosling, Jonathan;Plumb, Andrew;Emmanuel, Anton, V
背景：肛门括约肌功能的准确测量对确定常见盆底疾病的治疗方法具有潜在的价值。本研究的目的是通过与传统测压法（CM）进行比较，确定高分辨率肛门直肠测压法（HRAM）的可重复性并验证其有效性。从这项工作中产生的将是明确的正常范围数据。方法对80名健康志愿者（女性40名）进行重复性试验。使用站点拉通技术将16通道水灌注HRAM导管与8通道常规导管进行比较。关键结果高分辨率肛门直肠测压在测量静息压（组内相关系数[ICC] 0.73 vs 0.68，HRAM vs CM）和挤压增量（ICC 0.90 vs 0.94，HRAM vs CM）时与传统测压具有相似的精度。HRAM测得的静息压比CM低10%，挤压压比CM高27%。结论和推论高分辨率肛门直肠测压是一种有效的技术，具有与CM相当的精度。HRAM测量与CM有很大不同，必须使用一组新的正常值。
Background Accurate measurement of anal sphincter function is potentially of value in defining treatment of common pelvic floor disorders. The aim of this study was to establish repeatability and validate high-resolution anorectal manometry (HRAM) by comparison to conventional manometry (CM). Arising from this work would be definitive normal range data. Methods Eighty healthy volunteers (40 female) underwent a test-retest repeatability study. A 16-channel water-perfused HRAM catheter was compared to an 8-channel conventional catheter using a station pull-through technique. Key Results High-resolution anorectal manometry had similar precision to conventional manometry when measuring resting pressure (intraclass correlation coefficient [ICC] 0.73 vs 0.68, HRAM vs CM) and squeeze increment (ICC 0.90 vs 0.94, HRAM vs CM). HRAM measured resting pressures 10% lower than CM and squeeze pressure 27% higher than CM. Conclusions and Inferences High-resolution anorectal manometry is a valid technique with comparable precision to CM. HRAM measurements differ considerably to CM, and a new set of normal values must be used.