Supramolecular host-guest interaction for labeling and detection of cellular biomarkers.
Supramolecular host-guest interaction for labeling and detection of cellular biomarkers.
复制标题
用于标记和检测细胞生物标志物的超分子宿主 - 宿主相互作用。
DOI:
10.1002/anie.201105670
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发表时间:
2012-01-09
期刊:
影响因子:
--
通讯作者:
Weissleder R
中科院分区:
文献类型:
--
作者:
Agasti SS;Liong M;Tassa C;Chung HJ;Shaw SY;Lee H;Weissleder R
Be my guest: A supramolecular host–guest interaction is utilized for highly efficient bioorthogonal labeling of cellular targets. Antibodies labeled with a cyclodextrin host molecule bind to adamantane-labeled magnetofluorescent nanoparticles (see picture) and provide an amplifiable strategy for biomarker detection that can be adapted to different diagnostic techniques such as molecular profiling or magnetic cell sorting.