Supramolecular host-guest interaction for labeling and detection of cellular biomarkers.

Supramolecular host-guest interaction for labeling and detection of cellular biomarkers.
复制标题

用于标记和检测细胞生物标志物的超分子宿主 - 宿主相互作用。

DOI:
10.1002/anie.201105670
复制
发表时间:
2012-01-09
期刊:
Angewandte Chemie (International ed. in English)
影响因子:
--
通讯作者:
Weissleder R
Weissleder R
中科院分区:
其他
文献类型:
--
作者:
Agasti SS;Liong M;Tassa C;Chung HJ;Shaw SY;Lee H;Weissleder R

文献摘要

被引文献

相似文献

Be my guest:超分子主客体相互作用用于高效生物正交标记细胞靶点。用环糊精主体分子标记的抗体与金刚烷标记的磁荧光纳米颗粒结合(见图),并为生物标志物检测提供了一种可简化的策略,该策略可适用于不同的诊断技术,如分子分析或磁性细胞分选。
Be my guest: A supramolecular host–guest interaction is utilized for highly efficient bioorthogonal labeling of cellular targets. Antibodies labeled with a cyclodextrin host molecule bind to adamantane-labeled magnetofluorescent nanoparticles (see picture) and provide an amplifiable strategy for biomarker detection that can be adapted to different diagnostic techniques such as molecular profiling or magnetic cell sorting.