Light-induced release of A2E photooxidation toxic products from lipofuscin granules of human retinal pigment epithelium
Light-induced release of A2E photooxidation toxic products from lipofuscin granules of human retinal pigment epithelium
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DOI：
10.1134/s1607672909020112
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发表时间：
2009-04-01
影响因子：
0.8
通讯作者：
Ostrovsky, M. A.
中科院分区：
文献类型：
--
作者：
Dontsov, A. E.;Sakina, N. L.;Ostrovsky, M. A.
一项研究表征了脂褐素颗粒光氧化获得的产物，并评估了它们从颗粒扩散到水溶性部分的能力。数据发现，A2E光氧化产物极有可能参与了年龄相关性黄斑变性的发展。
A study characterized the products obtained as a result of photooxidation of lipofuscin granules and to assess their ability to diffuse from the granule to the water-soluble fraction. Data found it highly likeley that A2E photooxidation products may be involved in the development of age-related macular degeneration.