Secretion and crinophagy in prolactin cells.
Secretion and crinophagy in prolactin cells.
复制标题
催乳素细胞的分泌和自噬。
DOI：
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发表时间：
1977
影响因子：
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通讯作者：
M. Farquhar
中科院分区：
文献类型：
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作者：
M. Farquhar
促乳细胞或催乳素分泌细胞由于其独特的精细结构、大颗粒和在体外可持续存活，一直是研究垂体分泌及其调控机制的理想对象。在这篇评论中，催乳素分泌的结构基础进行了总结，并提出了催乳素分泌的细胞内事件的顺序与它们的位置进行了概述。现有的证据验证催乳素分泌的各个步骤和它们的调节进行了总结。最后，一些未解决的问题，为未来留下的针。
The mammotroph or prolactin-secreting cell, due to its distinctive fine structure, large granules, and sustained survival in vitro, has been a favorite object for studying mechanisms of pituitary secretion and its control. In this review the structural basis of prolactin secretion is summarized and the proposed sequence of intracellular events involved in prolactin secretion together with their site of loaction is outlined. The available evidence validating the various steps in prolactin secretion and their regulation is summarized. Finally, some of the unresolved problems remaining for the future are pinpointed.