The efficacy of a brief alcohol intervention combined with %CDT feedback in patients being treated for type 2 diabetes and/or hypertension
The efficacy of a brief alcohol intervention combined with %CDT feedback in patients being treated for type 2 diabetes and/or hypertension
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DOI：
10.15288/jsa.2004.65.631
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发表时间：
2004-09-01
期刊：
影响因子：
--
通讯作者：
Brown, D
中科院分区：
文献类型：
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作者：
Fleming, M;Brown, R;Brown, D
目的：正在开发酒精生物标志物，以提高医生识别和干预患有慢性医疗问题的患者受到大量饮酒的影响。本文报告了一项简短干预试验的发现，其中包括向患者的碳水化合物缺陷转铁蛋白（CDT）测试结果的反馈。方法：进行了一项试点研究，以测试简短临床医生建议的功效，以减少酒精使用并改善151例接受2型糖尿病和高血压治疗的患者的健康状况。干预措施包括通知患者CDT水平。患者被随机分配为通常的护理或简短的干预组。结果：两组在酒精使用，CDT水平，成瘾率，年龄，性别，社会经济状况或健康状况指标的基线时没有显着差异。在短暂的干预之后，在饮酒和CDT的干预组中观察到显着差异：在12个月的随访中，重量饮酒者的比例比基线从35.8％下降到干预组的24.7％，没有变化对照组（P
Objective: Alcohol biomarkers are being developed to improve a physician's ability to identify and intervene with patients with chronic medical problems adversely affected by heavy alcohol use. This article reports the findings of a brief intervention trial which included feedback to patients of their carbohydrate-deficient transferrin (CDT) test results. Method: A pilot study was conducted to test the efficacy of brief clinician advice to reduce alcohol use and improve health status in a sample of 151 patients being treated for Type 2 diabetes and hypertension. The intervention included informing patients of their CDT levels. The patients were randomized to a usual care or brief intervention group. Results: There were no significant differences at baseline between the two groups in alcohol use, CDT levels, addiction rates, age, gender, socioeconomic status or health status measures. Following brief intervention, significant differences were observed in the intervention group in alcohol use and CDT: The proportion of heavy drinkers at the 12-month follow-up compared with baseline decreased from 35.8% to 24.7% in the intervention group, with no change in the control group (p