Life-years gained from modern cardiological treatments and population risk factor changes in England and Wales, 1981-2000
Life-years gained from modern cardiological treatments and population risk factor changes in England and Wales, 1981-2000
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DOI：
10.2105/ajph.2003.029579
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发表时间：
2005-01-01
影响因子：
12.7
通讯作者：
Capewell, S
中科院分区：
文献类型：
--
作者：
Ünal, B;Critchley, JA;Capewell, S
目标.我们估计了1981年至2000年间英格兰和威尔士心脏病治疗和心血管危险因素变化所获得的生命年。我们使用IMPACT模型整合了冠心病患者数量、治疗吸收和有效性、危险因素趋势和冠心病患者中位生存期的数据。与1981年相比，2000年的冠心病死亡人数减少了68230人。在25-84岁人群中获得了约925415生命年（范围：745195-1138655）。患者的心脏病治疗约增加了194145生命年（范围：142505-259225），人群危险因素变化约增加了731270生命年（范围：602695-879430）。主要危险因素的适度减少导致生命年的增加比心脏病治疗高4倍。促进健康饮食和体育活动的有效政策可能会取得更大的成果。
Objectives. We estimated life-years gained from cardiological treatments and cardiovascular risk factor changes in England and Wales between 1981 and 2000.Methods. We used the IMPACT model to integrate data on the number of coronary heart disease patients, treatment uptake and effectiveness, risk factor trends, and median survival in coronary heart disease patients.Results. Compared with 1981, there were 68230 fewer coronary deaths in 2000. Approximately 925415 life-years were gained among people aged 25-84 years (range: 745195-1138655). Cardiological treatments for patients accounted for approximately 194145 life-years gained (range: 142505-259225), and population risk factor changes accounted for approximately 731270 life-years gained (range: 602695-879430).Conclusions. Modest reductions in major risk factors led to gains in life-years 4 times higher than did cardiological treatments. Effective policies to promote healthy diets and physical activity might achieve even greater gains.