High incidence of cytomegalovirus reactivation in adult recipients of an unrelated cord blood transplant.
High incidence of cytomegalovirus reactivation in adult recipients of an unrelated cord blood transplant.
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发表时间：
2005
期刊：
影响因子：
10.1
通讯作者：
A. Takami;K. Mochizuki;H. Asakura;H. Yamazaki;H. Okumura;S. Nakao
中科院分区：
文献类型：
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作者：
A. Takami;K. Mochizuki;H. Asakura;H. Yamazaki;H. Okumura;S. Nakao
对巨细胞病毒（CMV）血清阳性成人移植受者的回顾性分析显示，10/10（100%）无关脐带血受者、17/39（43%）相关匹配供体移植受者、16/23（79%）无关匹配供体移植受者在移植后发生CMV抗原血症，8/12例（67%）接受了不匹配的相关供体移植。这些结果表明，无关的脐带血移植本身可能与高发病率的巨细胞病毒再激活。
This retrospective analysis of cytomegalovirus (CMV)-seropositive adult transplant recipients showed that CMV antigenemia occurred after transplantation in 10/10 (100%) recipients of unrelated cord blood, 17/39 (43%) recipients of a related matched donor graft, 16/23 (79%) recipients of an unrelated matched donor graft, and 8/12 (67%) recipients of a mismatched related donor graft. These results suggest that unrelated cord blood transplantation itself may be correlated with a high incidence of CMV reactivation.