Pericytic porters: helping leptin step in.
Pericytic porters: helping leptin step in.
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DOI:
10.1016/j.tem.2021.08.001
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发表时间:
2021-12
期刊:
影响因子:
--
通讯作者:
Pitts MW
中科院分区:
文献类型:
--
作者:
Torres DJ;Pitts MW
A new mechanism of leptin extravasation from the bloodstream into the brain may have been discovered. According to recent findings by Butiaeva et al., pericytes within the blood–brain barrier (BBB) express the leptin receptor and, upon activation, facilitate the movement of the appetite-suppressing hormone into deeper regions of the hypothalamus.
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