Evaluation of antibiotic self-medication among outpatients of the state university hospital of Port-Au-Prince, Haiti: a cross-sectional study.
Evaluation of antibiotic self-medication among outpatients of the state university hospital of Port-Au-Prince, Haiti: a cross-sectional study.
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DOI：
10.11604/pamj.2017.28.4.12589
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Henrys JH
中科院分区：
文献类型：
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作者：
Moise K;Bernard JJ;Henrys JH
在海地，所有药物都可以在柜台购买，自行服用抗生素似乎是一种常见做法。 β-内酰胺类和大环内酯类药物的不当使用可能会导致抗菌素耐药性的产生。本研究旨在（i）评估抗生素自我药疗的程度，（ii）探讨影响因素（年龄、性别和教育背景），以及（iii）确定在太子港州立大学医院门诊就诊的患者使用的特定抗生素药物类别。 2014年12月，对太子港国立大学医院的200名门诊患者进行了一项横断面调查。采用标准化问卷进行面对面访谈。儿科患者的家长可以代表他们回答问题。在研究样本中，45.5%的人自行使用抗生素进行药物治疗。在教育程度最高的患者中，这种情况较少见（23.1%；OR：0.89（0.5-1.75），p = 0.001）。轻微症状（28.6%）和阴道瘙痒（44.4%）是自行使用抗生素的主要原因。 67.0% 的人报告使用阿莫西林进行自我药疗。自行服用抗生素是海地患者的常见做法，并且在受教育程度较低的人群中更为常见。阿莫西林是治疗尿路感染最常用的药物。提高人们对这种做法危险性的认识并执行有关使用非处方抗生素的现行法律至关重要。
In Haiti, where all drugs are available over the counter, self-medication with antibiotics appears as a common practice. Inappropriate use of beta-lactams and macrolides is likely to contribute to the development of antimicrobial resistance. This study aimed to (i) assess the extent of self-medication with antibiotics, (ii) explore the contributing factors (age, gender and educational background) and (iii) identify specific antibiotic drug classes used among patients attending the outpatient clinic of the State University Hospital of Port-au-Prince. A cross-sectional survey among 200 outpatients of the State University Hospital of Port-au-Prince was conducted in December 2014. Face-to-face interviews were conducted using a standardized questionnaire. Parents of pediatric patients were allowed to answer to questions on their behalf. Among the study sample, 45.5% practiced self-medication with antibiotics. It was less prevalent among patients with the highest education level (23.1%; OR: 0.89 (0.5-1.75), p = 0.001). Mild symptoms (28.6%) and vaginal itching (44.4%) were the main reasons for self-medication with antibiotics. Self-medication using amoxicillin was reported by 67.0%. Self-medication with antibiotics is a common practice among Haitian patients and is more common among the less educated. Amoxicillin for urinary tract infections is the most commonly used medication. It is crucial to raise awareness on the dangers of the practice in the population and inforce the current law regarding the use of over the counter antibiotics.