Surface Engineering to Boost the Performance of Nanoparticle-Based T-1 Contrast Agents
Surface Engineering to Boost the Performance of Nanoparticle-Based T-1 Contrast Agents
复制标题
表面工程提高纳米颗粒 T-1 造影剂的性能
DOI：
10.1002/ejic.201900697
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发表时间：
2019
影响因子：
2.3
通讯作者：
Gao Jinhao
中科院分区：
文献类型：
--
作者：
Lin Hongyu;Liu Kun;Gao Jinhao
在目前用于磁共振成像（MRI）的钆基造影剂（CAs）的替代品中，纳米颗粒基t1cas由于其更好的生物相容性和适应性而引起了广泛的关注。近年来，表面工程已成为提高纳米颗粒基t1cas性能的一种有效而有前途的方法。在这篇综述中，我们总结和分类了几项利用表面工程的代表性作品的具体策略，希望能激发更多的想法和努力来发展这种方法，最终有利于MRI CAs的发展。
In the alternatives to current gadolinium‐based contrast agents (CAs) for magnetic resonance imaging (MRI), nanoparticle‐basedT1CAs have drawn extensive attention due to their better biocompatibility and adaptability. Recently, surface engineering has emerged as an efficient and promising method to promote the performance of nanoparticle‐basedT1CAs. In this Minireview, we sum up and categorize the specific strategies of several representative works that utilize surface engineering and hope to stimulate more ideas and efforts for the development of this method, which will eventually benefit the advancement of MRI CAs.