Mucinous Neoplasms of the Ovary: Radiologic-Pathologic Correlation
Mucinous Neoplasms of the Ovary: Radiologic-Pathologic Correlation
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DOI：
10.1148/rg.2019180221
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发表时间：
2019-07-01
期刊：
影响因子：
5.5
通讯作者：
Wolfman, Darcy J.
中科院分区：
文献类型：
--
作者：
Marko, Jamie;Marko, Kathryn, I;Wolfman, Darcy J.
卵巢粘液性肿瘤占卵巢肿瘤的10%~15%。它们可能是良性的、交界性的或恶性的。绝大多数为良性或交界性，分别占80%和16%~17%。卵巢粘液性肿瘤多见于20-40岁的女性。临床表现无特异性，但大多数卵巢粘液性肿瘤表现为单侧巨大的盆腔肿块。大体病理分析，粘液性卵巢肿瘤表现为大的多房性囊性肿块。囊腔的内容因内部粘蛋白含量的不同而不同。在组织学分析中，粘液性卵巢肿瘤由多个囊泡组成，内衬粘液上皮，通常类似于胃肠型上皮。影像评估通常包括US和/或MRI。影像表现与大体病理特征相似，包括一个大的、单侧的、多房的囊性肿块。囊性囊性肿块的回声、密度和信号强度随粘蛋白含量的不同而不同。卵巢粘液性肿瘤采用FIGO(国际妇产科联合会)分期系统进行手术分期。主要治疗方法是手术治疗，在罕见的粘液性癌合并卵巢外疾病的病例中考虑辅助化疗。由于大多数粘液性卵巢肿瘤是良性或交界性的，总体预后良好。
Mucinous neoplasms of the ovary account for 10%-15% of ovarian neoplasms. They may be benign, borderline, or malignant. The large majority are benign or borderline, accounting for 80% and 16%-17%, respectively. Mucinous neoplasms of the ovary most commonly affect women in their 20s to 40s.The clinical manifestation is nonspecific, but most mucinous ovarian neoplasms manifest as large unilateral pelvic masses. At gross pathologic analysis, mucinous ovarian neoplasms appear as large multiloculated cystic masses. The contents of the cyst loculi vary on the basis of differences in internal mucin content. At histologic analysis, mucinous ovarian neoplasms are composed of multiple cysts lined by mucinous epithelium, often resembling gastrointestinal-type epithelium. Imaging evaluation most commonly includes US and/or MRI. The imaging findings parallel the gross pathologic features and include a large, unilateral, multiloculated cystic mass.The cyst loculi vary in echogenicity, attenuation, and signal intensity depending on the mucin content. Mucinous neoplasms of the ovary are staged surgically using the FIGO (International Federation of Gynecology and Obstetrics) staging system. Primary treatment is surgical, with adjuvant chemotherapy considered in the uncommon case of mucinous carcinoma with extraovarian disease. Since most mucinous ovarian neoplasms are benign or borderline, the overall prognosis is excellent.