Copper-Catalyzed Amidation of 2-Phenylpyridine with Oxygen as the Terminal Oxidant

Copper-Catalyzed Amidation of 2-Phenylpyridine with Oxygen as the Terminal Oxidant
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DOI:
10.1021/jo200409h
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发表时间:
2011-05-20
影响因子:
3.6
通讯作者:
Nicholas, Kenneth M.
Nicholas, Kenneth M.
中科院分区:
化学2区
文献类型:
--
作者:
John, Alex;Nicholas, Kenneth M.

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报道了Cu(OAc)(2)催化的O-2介导的C-H键活化的2-苯基吡啶酰胺化反应。各种含氮试剂,包括磺酰胺、羧酰胺和苯胺,以中等至良好的产率参与反应。
The Cu(OAc)(2)-catalyzed, O-2-mediated amidation of 2-phenylpyridine via C-H bond activation is reported. A variety of nitrogen reagents including sulfonamides, carboxamides, and anilines participate in the reaction in moderate to good yields.