Antitubercular constituents from the hexane fraction of Morinda citrifolia Linn. (Rubiaceae)

Antitubercular constituents from the hexane fraction of Morinda citrifolia Linn. (Rubiaceae)
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DOI:
10.1002/ptr.1003
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发表时间:
2002-11-01
影响因子:
7.2
通讯作者:
Aguinaldo, AM
Aguinaldo, AM
中科院分区:
医学2区
文献类型:
--
作者:
Saludes, JP;Garson, MJ;Aguinaldo, AM

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桑葚粗乙醇提取物和己烷部分。(茜草科)显示抗结核活性。正己烷部分的主要成分是e -叶绿醇、环蒿醇、豆甾醇、-谷甾醇、油菜-5,7,22-三烯-3-醇和酮类固醇豆甾醇-4-烯-3- 1和豆甾醇-4-22-二烯-3- 1。e -叶绿醇,两种酮类固醇的混合物,以及从油菜中提取的附二氧甾醇-5,7,22-三烯-3 - β -醇都显示出明显的抗结核活性。版权所有:John Wiley Sons, Ltd。
A crude ethanol extract and hexane fraction from Morinda citrifolia Linn. (Rubiaceae) show antitubercular activity. The major constituents of the hexane fraction are E-phytol, cycloartenol, stigmasterol, beta-sitosterol, campesta-5,7,22-trien-3beta-ol and the ketosteroids stigmasta-4-en-3-one and stigmasta-4-22-dien-3-one. E-Phytol, a mixture of the two ketosteroids, and the epidioxysterol derived from campesta-5,7,22-trien-3beta-ol all show pronounced antitubercular activity. Copyright (C) 2002 John Wiley Sons, Ltd.