GRANULAR-CELL TUMOR - AN ANALYSIS OF 16 CASES AND REVIEW OF THE LITERATURE

GRANULAR-CELL TUMOR - AN ANALYSIS OF 16 CASES AND REVIEW OF THE LITERATURE
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DOI:
10.1016/s0190-9622(81)70085-9
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发表时间:
1981-01-01
影响因子:
13.8
通讯作者:
APISARNTHANARAX, P
APISARNTHANARAX, P
中科院分区:
医学1区
文献类型:
--
作者:
APISARNTHANARAX, P

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1964年至1979年期间,共观察到16例颗粒细胞瘤。这些患者的医学资料显示,平均发病年龄为39岁,黑人(69%)和女性患者(62.5%)的发病率较高。最常见的体征(16例患者中有12例)是无症状的肿块。16例患者共88个肿瘤; 74个发生在皮肤,6个发生在口腔,2个发生在乳房和会阴,1个发生在喉、腮腺、眼睑和阑尾。4例患者(25%)发现多发性肿瘤,均为黑人。这种肿瘤的组织发生仍有争议,但似乎有利于多潜能未分化间充质细胞起源的理论。
Sixteen patients with granular cell tumors were seen between 1964 and 1979. The medical data of these patients showed an average age incidence of 39 yr and a greater frequency anong Negroes (69%) and in female patients (62.5%). The most common sign (in 12 of 16 patients) was the presence of an asymptomatic mass. There was a total of 88 tumors in 16 patients; 74 arose in the skin, 6 in the oral cavity, 2 each in the breast and perineum and 1 each in the larynx, parotid gland, eyelid and appendix. Multiple tumors were noted in 4 patients (25%), all of whom were Negroes. The histogenesis of this tumor is still controversial but appears to favor the theory of multipotential undifferentiated mesenchymal cell origin.